Searchable abstracts of presentations at key conferences in endocrinology

ea0099p502 | Endocrine-Related Cancer | ECE2024

Ovarian neuroendocrine tumor metastases can induce estrogen production in postmenopausal patients

Mulders Merijn , van Velthuysen M F , Roes Eva Maria , Hofland Leo , de Herder Wouter W , Hofland Hans

Background: Neuroendocrine tumors (NET) are malignant neoplasms that can be associated with specific hormonal syndromes. We describe a novel syndrome of postmenopausal vaginal bleeding and ovarian estradiol overproduction due to ovarian NET localizations.Methods: A clinical workup was performed for 2 index patients with ovarian metastases of small bowel neuroendocrine tumors and symptoms of postmenopausal vaginal bleeding. Ovarian tissue was collected af...