ea0099p502 | Endocrine-Related Cancer | ECE2024
Mulders Merijn
, van Velthuysen M F
, Roes Eva Maria
, Hofland Leo
, de Herder Wouter W
, Hofland Hans
Background: Neuroendocrine tumors (NET) are malignant neoplasms that can be associated with specific hormonal syndromes. We describe a novel syndrome of postmenopausal vaginal bleeding and ovarian estradiol overproduction due to ovarian NET localizations.Methods: A clinical workup was performed for 2 index patients with ovarian metastases of small bowel neuroendocrine tumors and symptoms of postmenopausal vaginal bleeding. Ovarian tissue was collected af...